List of scores for physical traits
In the table below, polygenic scores are sorted in ascending alphabetical order of trait, then variable name.
As well as scrolling and searching alphabetically, you can use your web browser's search facilities (Ctrl+F) to search for key words.
Trait: Alzheimer's Disease, Trait category: Physical Health
Variable name: Alzheimers_Lambert2013, LDpred version: 1
Number of SNPs coordinated: , Sample size: 54162 (17008 cases, 37154 controls)
Heritability (h2): 0.07, Standard error (se): 0.01, Z-score (h2/se): 7
Published study: https://www.nature.com/articles/ng.2802, Publication year: 2013
Trait: Alzheimer's Disease family history - maternal, Trait category: Physical Health
Variable name: AlzheimersMaternal_Marioni2018, LDpred version: 1
Number of SNPs coordinated: 500706, Sample size: 314278 (27696 cases, 286582 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/s41398-018-0150-6, Publication year: 2018
Trait: Alzheimer's Disease family history - meta-analysis of IGAP, maternal & paternal, Trait category: Physical Health
Variable name: AlzheimersMetaIGAP_Marioni2018, LDpred version: 1
Number of SNPs coordinated: 500706, Sample size: 388324 (67614 cases, 320710 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/s41398-018-0150-6, Publication year: 2018
Trait: Alzheimer's Disease family history - paternal, Trait category: Physical Health
Variable name: AlzheimersPaternal_Marioni2018, LDpred version: 1
Number of SNPs coordinated: 500706, Sample size: 314278 (14338 cases, 299940 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/s41398-018-0150-6, Publication year: 2018
Trait: Asthma, Trait category: Physical Health
Variable name: Asthma_Moffatt2007, LDpred version: 1
Number of SNPs coordinated: 241364, Sample size: 26475 (10365 cases, 16110 controls)
Heritability (h2): 0.1064, Standard error (se): 0.0239, Z-score (h2/se): 4.5
Published study: https://www.ncbi.nlm.nih.gov/pubmed/17611496, Publication year: 2007
Trait: Asthma diagnosed by doctor, Trait category: Physical Health
Variable name: Doctor_diagnosed_asthma_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 83529 (10589 cases, 72940 controls)
Heritability (h2): 0.1568, Standard error (se): 0.0302, Z-score (h2/se): 5.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Asthma: diagnosed by doctor, Trait category: Physical Health
Variable name: Asthma_diagnosed_by_doctor_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336782 (38791 cases, 297991 controls)
Heritability (h2): 0.1724, Standard error (se): 0.0139, Z-score (h2/se): 12.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: back problem (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_back_problem_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337168 (5910 cases, 331258 controls)
Heritability (h2): 0.0698, Standard error (se): 0.0193, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: coxarthrosis [arthrosis of hip]: diagnosis ICD10: M16 , Trait category: Physical Health
Variable name: Coxarthrosis_ICD10_M16_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (4934 cases, 332265 controls)
Heritability (h2): 0.1394, Standard error (se): 0.0309, Z-score (h2/se): 4.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: dorsalgia: diagnosis ICD10: M54 , Trait category: Physical Health
Variable name: Dorsalgia_ICD10_M54_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (5660 cases, 331539 controls)
Heritability (h2): 0.091, Standard error (se): 0.0206, Z-score (h2/se): 4.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: gonarthrosis [arthrosis of knee]: diagnosis ICD10: M17 , Trait category: Physical Health
Variable name: Gonarthrosis_ICD10_M17_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336929 (6560 cases, 330369 controls)
Heritability (h2): 0.1199, Standard error (se): 0.0221, Z-score (h2/se): 5.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: gout (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_gout_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (4807 cases, 332352 controls)
Heritability (h2): 0.2398, Standard error (se): 0.0658, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: leg pain on walking, Trait category: Physical Health
Variable name: Leg_pain_on_walking_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 110337 (24101 cases, 86236 controls)
Heritability (h2): 0.1339, Standard error (se): 0.0143, Z-score (h2/se): 9.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: mononeuropathies of upper limb: diagnosis ICD10: G56 , Trait category: Physical Health
Variable name: Mononeuropathies_of_upper_limb_ICD10_G56_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (5886 cases, 331313 controls)
Heritability (h2): 0.1498, Standard error (se): 0.0243, Z-score (h2/se): 6.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: osteoarthritis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_osteoarthritis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (28257 cases, 308902 controls)
Heritability (h2): 0.0678, Standard error (se): 0.00841, Z-score (h2/se): 8.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Back/limb/skeletal: osteoporosis (heel bone mineral density), Trait category: Physical Health
Variable name: BoneMinDen_Kemp2017, LDpred version: 1
Number of SNPs coordinated: 499989, Sample size: 142487
Heritability (h2): 0.36, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/ng.3949, Publication year: 2017
Note: summary stats formatted because LDpred cannot handle very small pvalues (pval less than 0.00000001 recoded as 0.00000001)
Trait: Back/limb/skeletal: rheumatoid Arthritis, Trait category: Physical Health
Variable name: RA_Okada2014, LDpred version: 1
Number of SNPs coordinated: 494198, Sample size: 103638 (29880 cases, 73758 controls)
Heritability (h2): 0.16, Standard error (se): 0.02, Z-score (h2/se): 8
Published study: https://www.ncbi.nlm.nih.gov/pubmed/24390342, Publication year: 2014
Trait: balding Pattern 2, Trait category: Physical Health
Variable name: Hair_balding_pattern2_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 165649 (38044 cases, 127605 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: balding Pattern 3, Trait category: Physical Health
Variable name: Hair_balding_pattern3_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 165649 (44304 cases, 121345 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: balding Pattern 4, Trait category: Physical Health
Variable name: Hair_balding_pattern4_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 165649 (30225 cases, 135424 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: Brain: cortex global thickness, Trait category: Physical Health
Variable name: cortex_global_thickness_Grasby2020, LDpred version: 2
Number of SNPs coordinated: 1068699, Sample size: 33992
Heritability (h2): 0.26, Standard error (se): 0.02, Z-score (h2/se): 13
Published study: https://pubmed.ncbi.nlm.nih.gov/32193296/, Publication year: 2020
Note: Genomic control correction was applied.
Trait: Brain: cortical surface area, Trait category: Physical Health
Variable name: cortical_surface_area_Grasby2020, LDpred version: 2
Number of SNPs coordinated: 1066953, Sample size: 33992
Heritability (h2): 0.34, Standard error (se): 0.03, Z-score (h2/se): 11.3
Published study: https://pubmed.ncbi.nlm.nih.gov/32193296/, Publication year: 2020
Note: Genomic control correction was applied.
Trait: Brain: mean Caudate, Trait category: Physical Health
Variable name: MeanCaudate_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.25, Standard error (se): 0.0383, Z-score (h2/se): 6.5
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Brain: mean Hippocampus, Trait category: Physical Health
Variable name: MeanHippocampus_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.1413, Standard error (se): 0.0385, Z-score (h2/se): 3.7
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Brain: mean Pallidum, Trait category: Physical Health
Variable name: MeanPallidum_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.16, Standard error (se): 0.0409, Z-score (h2/se): 3.9
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Brain: mean Putamen, Trait category: Physical Health
Variable name: MeanPutamen_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.2933, Standard error (se): 0.0435, Z-score (h2/se): 6.7
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Brain: mean Thalamus, Trait category: Physical Health
Variable name: MeanThalamus_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.1389, Standard error (se): 0.0352, Z-score (h2/se): 3.9
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Cancer code, self-reported: basal cell carcinoma, Trait category: Physical Health
Variable name: Cancer_self_reported_BCC_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3156 cases, 334003 controls)
Heritability (h2): 0.1491, Standard error (se): 0.0412, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cancer code, self-reported: breast cancer, Trait category: Physical Health
Variable name: Cancer_self_reported_breast_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (7480 cases, 329679 controls)
Heritability (h2): 0.1104, Standard error (se): 0.0221, Z-score (h2/se): 5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cancer diagnosed by doctor, Trait category: Physical Health
Variable name: Cancer_diagnosed_by_doctor_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336272 (26576 cases, 309696 controls)
Heritability (h2): 0.0296, Standard error (se): 0.00829, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cancer: malignant neoplasm of breast: diagnosis ICD10: C50 , Trait category: Physical Health
Variable name: Breast_neoplasm_ICD10_C50_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (5510 cases, 331689 controls)
Heritability (h2): 0.1144, Standard error (se): 0.0239, Z-score (h2/se): 4.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cancer: number of self-reported cancers, Trait category: Physical Health
Variable name: Number_of_self_reported_cancers_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199
Heritability (h2): 0.0085, Standard error (se): 0.00243, Z-score (h2/se): 3.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cancer: other malignant neoplasms of skin: diagnosis ICD10: C44 , Trait category: Physical Health
Variable name: Skin_neoplasm_ICD10_C44_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (4826 cases, 332373 controls)
Heritability (h2): 0.1195, Standard error (se): 0.0322, Z-score (h2/se): 3.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: blood pressure medication, Trait category: Physical Health
Variable name: Blood_pressure_medication_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 180203 (31488 cases, 148715 controls)
Heritability (h2): 0.2403, Standard error (se): 0.0175, Z-score (h2/se): 13.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: chest pain or discomfort, Trait category: Physical Health
Variable name: Chest_pain_or_discomfort_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 334053 (51937 cases, 282116 controls)
Heritability (h2): 0.0774, Standard error (se): 0.00591, Z-score (h2/se): 13.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: chest pain or discomfort walking normally, Trait category: Physical Health
Variable name: Chest_pain_or_discomfort_walking_normally_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 51475 (8816 cases, 42659 controls)
Heritability (h2): 0.1555, Standard error (se): 0.0318, Z-score (h2/se): 4.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: chest pain: Angina, Trait category: Physical Health
Variable name: Vascular_Angina_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 340159 (11372 cases, 349048 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: Cardiovascular: chest pain: Angina pectoris: diagnosis ICD10: I20 , Trait category: Physical Health
Variable name: Angina_pectoris_ICD10_I20_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (4837 cases, 332362 controls)
Heritability (h2): 0.1091, Standard error (se): 0.0266, Z-score (h2/se): 4.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: cholesterol lowering medication, Trait category: Physical Health
Variable name: Cholesterol_lowering_medication_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 154702 (35840 cases, 118862 controls)
Heritability (h2): 0.1381, Standard error (se): 0.0136, Z-score (h2/se): 10.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: coronary Artery Disease, Trait category: Physical Health
Variable name: CAD_Nikpay2015, LDpred version: 1
Number of SNPs coordinated: 499387, Sample size: 184305 (60801 cases, 123504 controls)
Heritability (h2): 0.07, Standard error (se): 0.005, Z-score (h2/se): 14
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26343387, Publication year: 2015
Trait: Cardiovascular: HDL Cholesterol, Trait category: Physical Health
Variable name: HDL_GLGC2013, LDpred version: 1
Number of SNPs coordinated: 439526, Sample size: 188577
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/ng.2797, Publication year: 2013
Trait: Cardiovascular: heart attack (vascular and heart problems diagnosed by doctor), Trait category: Physical Health
Variable name: Heart_attack_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 340159 (8288 cases, 352132 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: Cardiovascular: heart attack: Acute myocardial infarction: diagnosis ICD10: I21 , Trait category: Physical Health
Variable name: Acute_myocardial_infarction_ICD10_I21_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (3927 cases, 333272 controls)
Heritability (h2): 0.1081, Standard error (se): 0.0302, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: heart attack/myocardial infarction (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_heart_attack_etc_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (7735 cases, 329424 controls)
Heritability (h2): 0.1458, Standard error (se): 0.0212, Z-score (h2/se): 6.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: heart: Atrial fibrillation and flutter: diagnosis ICD10: I48 , Trait category: Physical Health
Variable name: Atrial_fibrillation_and_flutter_ICD10_I48_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (3818 cases, 333381 controls)
Heritability (h2): 0.1197, Standard error (se): 0.0344, Z-score (h2/se): 3.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: heart: Chronic ischaemic heart disease: diagnosis ICD10: I25 , Trait category: Physical Health
Variable name: Chronic_ischaemic_heart_disease_ICD10_I25_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (8755 cases, 328444 controls)
Heritability (h2): 0.1309, Standard error (se): 0.0247, Z-score (h2/se): 5.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Cardiovascular: heart: Resting Heart Rate, Trait category: Physical Health
Variable name: RestHeartRate_Eppinga, LDpred version: 1
Number of SNPs coordinated: 450000, Sample size: 265046
Heritability (h2): 0.212, Standard error (se): 0.002, Z-score (h2/se): 106
Published study: https://www.nature.com/articles/ng.3708, Publication year: 2016
Trait: Cardiovascular: high blood pressure (vascular and heart problems diagnosed by doctor), Trait category: Physical Health
Variable name: High_blood_pressure_UKB2019, LDpred version: 1
Number of SNPs coordinated: 433063, Sample size: 340159 (97139 cases, 263281 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2019
Trait: Cardiovascular: LDL Cholesterol, Trait category: Physical Health
Variable name: LDL_GLGC2013, LDpred version: 1
Number of SNPs coordinated: 439052, Sample size: 188577
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.nature.com/articles/ng.2797, Publication year: 2013
Trait: Current employment status: Unable to work because of sickness or disability, Trait category: Physical Health
Variable name: Unable_to_work_sickness_or_disability_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336252 (12554 cases, 323698 controls)
Heritability (h2): 0.1384, Standard error (se): 0.014, Z-score (h2/se): 9.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Diabetes diagnosed by doctor, Trait category: Physical Health
Variable name: Diabetes_diagnosed_by_doctor_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336473 (16183 cases, 320290 controls)
Heritability (h2): 0.2037, Standard error (se): 0.0163, Z-score (h2/se): 12.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Diabetes type 2, Trait category: Physical Health
Variable name: T2Diabetes_Scott2017, LDpred version: 1
Number of SNPs coordinated: 499770, Sample size: 159208 (26676 cases, 132532 controls)
Heritability (h2): -, Standard error (se): -, Z-score (h2/se): -
Published study: https://www.ncbi.nlm.nih.gov/pubmed/28566273, Publication year: 2017
Trait: DVT (Blood clot in the leg): diagnosed by doctor: , Trait category: Physical Health
Variable name: Blood_clot_in_leg_DVT_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336782 (6905 cases, 329877 controls)
Heritability (h2): 0.1063, Standard error (se): 0.024, Z-score (h2/se): 4.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Eyesight: cataract other: diagnosis ICD10: H26, Trait category: Physical Health
Variable name: Other_cataract_ICD10_H26_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (6025 cases, 331174 controls)
Heritability (h2): 0.0975, Standard error (se): 0.0239, Z-score (h2/se): 4.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Eyesight: cataract senile: diagnosis ICD10: H25 , Trait category: Physical Health
Variable name: Senile_cataract_ICD10_H25_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (2651 cases, 334548 controls)
Heritability (h2): 0.1352, Standard error (se): 0.0397, Z-score (h2/se): 3.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Eyesight: glaucoma (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_glaucoma_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3536 cases, 333623 controls)
Heritability (h2): 0.1248, Standard error (se): 0.0333, Z-score (h2/se): 3.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Fibroblastic disorders: diagnosis ICD10: M72 , Trait category: Physical Health
Variable name: Fibroblastic_disorders_ICD10_M72_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (1862 cases, 335337 controls)
Heritability (h2): 0.3527, Standard error (se): 0.117, Z-score (h2/se): 3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: benign neoplasm of colon, rectum, anus and anal canal: diagnosis ICD10: D12 , Trait category: Physical Health
Variable name: Benign_neoplasm_of_colon_rectum_anus_ICD10_D12_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (4794 cases, 332405 controls)
Heritability (h2): 0.1273, Standard error (se): 0.0263, Z-score (h2/se): 4.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: celiac Disease, Trait category: Physical Health
Variable name: Celiac_Dubois2010, LDpred version: 1
Number of SNPs coordinated: 226914, Sample size: 15283 (4533 cases, 10750 controls)
Heritability (h2): 0.31, Standard error (se): 0.05, Z-score (h2/se): 6.2
Published study: https://www.nature.com/articles/ng.543, Publication year: 2010
Trait: Gastrointestinal: cholelithiasis/gall stones (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_gall_stones_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (5573 cases, 331586 controls)
Heritability (h2): 0.0817, Standard error (se): 0.0228, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: cholelithiasis/gall stones: diagnosis ICD10: K80 , Trait category: Physical Health
Variable name: Cholelithiasis_ICD10_K80_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (6986 cases, 330213 controls)
Heritability (h2): 0.1097, Standard error (se): 0.0241, Z-score (h2/se): 4.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: crohns disease, Trait category: Physical Health
Variable name: Crohns_Liu2015, LDpred version: 1
Number of SNPs coordinated: 499588, Sample size: 27726 (5956 cases, 21770 controls)
Heritability (h2): 0.4799, Standard error (se): 0.0519, Z-score (h2/se): 9.2
Published study: https://www.nature.com/articles/ng.3359, Publication year: 2015
Trait: Gastrointestinal: diverticular disease of intestine: diagnosis ICD10: K57 , Trait category: Physical Health
Variable name: Diverticular_disease_of_intestine_ICD10_K57_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (6865 cases, 330334 controls)
Heritability (h2): 0.1052, Standard error (se): 0.0206, Z-score (h2/se): 5.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: diverticular disease/diverticulitis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_diverticular_disease_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3840 cases, 333319 controls)
Heritability (h2): 0.1514, Standard error (se): 0.0305, Z-score (h2/se): 5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: gastritis and duodenitis: diagnosis ICD10: K29 , Trait category: Physical Health
Variable name: Gastritis_and_duodenitis_ICD10_K29_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (8080 cases, 329119 controls)
Heritability (h2): 0.0574, Standard error (se): 0.0191, Z-score (h2/se): 3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: gastro-oesophageal reflux disease: diagnosis ICD10: K21 , Trait category: Physical Health
Variable name: Gastro-oesophageal_reflux_ICD10_K21_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (7282 cases, 329917 controls)
Heritability (h2): 0.0829, Standard error (se): 0.0166, Z-score (h2/se): 5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: haemorrhoids: diagnosis ICD10: I84 , Trait category: Physical Health
Variable name: Haemorrhoids_ICD10_I84_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (8190 cases, 329009 controls)
Heritability (h2): 0.0515, Standard error (se): 0.0164, Z-score (h2/se): 3.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Gastrointestinal: inflammatory bowel Disease, Trait category: Physical Health
Variable name: IBD_Liu2015, LDpred version: 1
Number of SNPs coordinated: 499609, Sample size: 34652 (12882 cases, 21770 controls)
Heritability (h2): 0.32, Standard error (se): 0.03, Z-score (h2/se): 10.7
Published study: https://www.nature.com/articles/ng.3359, Publication year: 2015
Trait: Gastrointestinal: primary biliary cirrhosis, Trait category: Physical Health
Variable name: PrimaryBiliaryCirrhosis_Cordell2015, LDpred version: 1
Number of SNPs coordinated: 358509, Sample size: 13239 (2764 cases, 10475 controls)
Heritability (h2): 0.3779, Standard error (se): 0.0596, Z-score (h2/se): 6.3
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26394269, Publication year: 2015
Trait: Gastrointestinal: ulcerative colitis, Trait category: Physical Health
Variable name: Colitis_Liu2015, LDpred version: 1
Number of SNPs coordinated: 499593, Sample size: 28738 (6968 cases, 21770 controls)
Heritability (h2): 0.2631, Standard error (se): 0.0294, Z-score (h2/se): 8.9
Published study: https://www.nature.com/articles/ng.3359, Publication year: 2015
Trait: Hayfever or allergic rhinitis diagnosed by doctor, Trait category: Physical Health
Variable name: hayfever_or_allergic_rhinitis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 83529 (18934 cases, 64595 controls)
Heritability (h2): 0.1637, Standard error (se): 0.026, Z-score (h2/se): 6.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hayfever, allergic rhinitis or eczema: allergy diagnosed by doctor: , Trait category: Physical Health
Variable name: Hayfever_allergic_rhinitis_eczema_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336782 (77891 cases, 258891 controls)
Heritability (h2): 0.1541, Standard error (se): 0.0138, Z-score (h2/se): 11.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hayfever/allergic rhinitis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_hayfever_etc_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (19320 cases, 317839 controls)
Heritability (h2): 0.0891, Standard error (se): 0.0134, Z-score (h2/se): 6.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: HbA1C (glycated haemoglobin), Trait category: Physical Health
Variable name: HbA1C_MAGIC2010, LDpred version: 1
Number of SNPs coordinated: 460208, Sample size: 46368
Heritability (h2): 0.0656, Standard error (se): 0.0109, Z-score (h2/se): 6
Published study: http://www.ncbi.nlm.nih.gov/pubmed/20858683, Publication year: 2010
Trait: Head: infant head circumference, Trait category: Physical Health
Variable name: HeadCircum_EGG2012, LDpred version: 1
Number of SNPs coordinated: 450869, Sample size: 10678
Heritability (h2): 0.24, Standard error (se): 0.04, Z-score (h2/se): 6
Published study: https://www.nature.com/articles/ng.2238, Publication year: 2012
Trait: Head: intercranial volume (ICV), Trait category: Physical Health
Variable name: ICV_Hibar2015, LDpred version: 1
Number of SNPs coordinated: 497525, Sample size: 30717
Heritability (h2): 0.1753, Standard error (se): 0.045, Z-score (h2/se): 3.9
Published study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/, Publication year: 2015
Trait: Headaches for 3+ months, Trait category: Physical Health
Variable name: Headaches_for_3_months_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 65583 (29979 cases, 35604 controls)
Heritability (h2): 0.0822, Standard error (se): 0.0177, Z-score (h2/se): 4.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hearing difficulty/problems with background noise, Trait category: Physical Health
Variable name: Hearing_difficulty_background_noise_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 330759 (125089 cases, 205670 controls)
Heritability (h2): 0.086, Standard error (se): 0.00553, Z-score (h2/se): 15.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hearing difficulty/problems: Yes, Trait category: Physical Health
Variable name: Hearing_difficulty_problems_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 323978 (84839 cases, 239139 controls)
Heritability (h2): 0.0757, Standard error (se): 0.00639, Z-score (h2/se): 11.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hearing: tinnitus: Yes, now most or all of the time, Trait category: Physical Health
Variable name: Tinnitus_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 109411 (7214 cases, 102197 controls)
Heritability (h2): 0.1368, Standard error (se): 0.0266, Z-score (h2/se): 5.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hernia: hiatus hernia (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_hiatus_hernia_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (7865 cases, 329294 controls)
Heritability (h2): 0.1057, Standard error (se): 0.0185, Z-score (h2/se): 5.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hernia: inguinal hernia: diagnosis ICD10: K40 , Trait category: Physical Health
Variable name: Inguinal_hernia_ICD10_K40_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (8815 cases, 328384 controls)
Heritability (h2): 0.1321, Standard error (se): 0.0205, Z-score (h2/se): 6.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hormone replacement therapy, Trait category: Physical Health
Variable name: Hormone_replacement_therapy_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 180203 (13365 cases, 166838 controls)
Heritability (h2): 0.0491, Standard error (se): 0.016, Z-score (h2/se): 3.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hormone replacement therapy: ever used hormone-replacement therapy (HRT), Trait category: Physical Health
Variable name: Ever_used_hormone_replacement_therapy_HRT_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 180631 (71377 cases, 109254 controls)
Heritability (h2): 0.0587, Standard error (se): 0.00813, Z-score (h2/se): 7.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hyperthyroidism/thyrotoxicosis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_hyperthyroidism_thyrotoxicosis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2547 cases, 334612 controls)
Heritability (h2): 0.1455, Standard error (se): 0.0443, Z-score (h2/se): 3.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Hypothyroidism/myxoedema (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_hypothyroidism_myxoedema_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (16376 cases, 320783 controls)
Heritability (h2): 0.2366, Standard error (se): 0.0253, Z-score (h2/se): 9.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Lupus: systemic lupus erythematosus, Trait category: Physical Health
Variable name: Lupus_Bentham2015, LDpred version: 1
Number of SNPs coordinated: 395436, Sample size: 23210 (7219 cases, 15991 controls)
Heritability (h2): 0.4142, Standard error (se): 0.071, Z-score (h2/se): 5.8
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26502338, Publication year: 2015
Trait: Maternal smoking around birth, Trait category: Physical Health
Variable name: maternal_smoking_around_birth_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 289727 (88601 cases, 201126 controls)
Heritability (h2): 0.0908, Standard error (se): 0.00638, Z-score (h2/se): 14.2
Published study: NA, Publication year: 2017
Trait: Medication: alendronate sodium (treatment/medication code), Trait category: Physical Health
Variable name: Medication_alendronate_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3773 cases, 333386 controls)
Heritability (h2): 0.1377, Standard error (se): 0.042, Z-score (h2/se): 3.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: allopurinol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_allopurinol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337139 (3819 cases, 333320 controls)
Heritability (h2): 0.247, Standard error (se): 0.0673, Z-score (h2/se): 3.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: amitriptyline (treatment/medication code), Trait category: Physical Health
Variable name: Medication_amitriptyline_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (6403 cases, 330756 controls)
Heritability (h2): 0.0675, Standard error (se): 0.0185, Z-score (h2/se): 3.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: amlodipine (treatment/medication code), Trait category: Physical Health
Variable name: Medication_amlodipine_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (13693 cases, 323466 controls)
Heritability (h2): 0.1143, Standard error (se): 0.0143, Z-score (h2/se): 8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: aspirin (treatment/medication code), Trait category: Physical Health
Variable name: Medication_aspirin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (45012 cases, 292147 controls)
Heritability (h2): 0.0525, Standard error (se): 0.00632, Z-score (h2/se): 8.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: atenolol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_atenolol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (13184 cases, 323975 controls)
Heritability (h2): 0.1003, Standard error (se): 0.013, Z-score (h2/se): 7.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: atorvastatin (treatment/medication code), Trait category: Physical Health
Variable name: Medication_atorvastatin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (10167 cases, 326992 controls)
Heritability (h2): 0.0882, Standard error (se): 0.0169, Z-score (h2/se): 5.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: bendroflumethiazide (treatment/medication code), Trait category: Physical Health
Variable name: Medication_bendroflumethiazide_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (19084 cases, 318075 controls)
Heritability (h2): 0.1349, Standard error (se): 0.0178, Z-score (h2/se): 7.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: cetirizine (treatment/medication code), Trait category: Physical Health
Variable name: Medication_cetirizine_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3821 cases, 333338 controls)
Heritability (h2): 0.1206, Standard error (se): 0.0284, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: citalopram (treatment/medication code), Trait category: Physical Health
Variable name: Medication_citalopram_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (5758 cases, 331401 controls)
Heritability (h2): 0.0831, Standard error (se): 0.0222, Z-score (h2/se): 3.7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: co-codamol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_co_codamol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (7861 cases, 329298 controls)
Heritability (h2): 0.0739, Standard error (se): 0.0175, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: diclofenac (treatment/medication code), Trait category: Physical Health
Variable name: Medication_diclofenac_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (7116 cases, 330043 controls)
Heritability (h2): 0.0868, Standard error (se): 0.0194, Z-score (h2/se): 4.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: doxazosin (treatment/medication code), Trait category: Physical Health
Variable name: Medication_doxazosin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3803 cases, 333356 controls)
Heritability (h2): 0.1443, Standard error (se): 0.0343, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: enalapril (treatment/medication code), Trait category: Physical Health
Variable name: Medication_enalapril_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2626 cases, 334533 controls)
Heritability (h2): 0.1722, Standard error (se): 0.0407, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: furosemide (treatment/medication code), Trait category: Physical Health
Variable name: Medication_furosemide_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2539 cases, 334620 controls)
Heritability (h2): 0.1207, Standard error (se): 0.0395, Z-score (h2/se): 3.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: gliclazide (treatment/medication code), Trait category: Physical Health
Variable name: Medication_gliclazide_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2807 cases, 334352 controls)
Heritability (h2): 0.1658, Standard error (se): 0.0396, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: glucosamine product (treatment/medication code), Trait category: Physical Health
Variable name: Medication_glucosamine_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (22914 cases, 314245 controls)
Heritability (h2): 0.0262, Standard error (se): 0.00833, Z-score (h2/se): 3.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: ibuprofen (treatment/medication code), Trait category: Physical Health
Variable name: Medication_ibuprofen_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (41952 cases, 295207 controls)
Heritability (h2): 0.0464, Standard error (se): 0.00581, Z-score (h2/se): 8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: insulin product (treatment/medication code), Trait category: Physical Health
Variable name: Medication_insulin_product_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3319 cases, 333840 controls)
Heritability (h2): 0.1117, Standard error (se): 0.0343, Z-score (h2/se): 3.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: lisinopril (treatment/medication code), Trait category: Physical Health
Variable name: Medication_lisinopril_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (9393 cases, 327766 controls)
Heritability (h2): 0.094, Standard error (se): 0.0163, Z-score (h2/se): 5.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: metformin (treatment/medication code), Trait category: Physical Health
Variable name: Medication_metformin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (8392 cases, 328767 controls)
Heritability (h2): 0.2106, Standard error (se): 0.0212, Z-score (h2/se): 9.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: None of the above (medication for cholesterol, blood pressure, diabetes, or take exogenous hormones), Trait category: Physical Health
Variable name: No_medication_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 180203 (124239 cases, 55964 controls)
Heritability (h2): 0.1127, Standard error (se): 0.00942, Z-score (h2/se): 12
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: Number of treatments/medications taken, Trait category: Physical Health
Variable name: Number_of_treatments_medications_taken_137_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199
Heritability (h2): 0.0598, Standard error (se): 0.00305, Z-score (h2/se): 19.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: omeprazole (treatment/medication code), Trait category: Physical Health
Variable name: Medication_omeprazole_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (19668 cases, 317491 controls)
Heritability (h2): 0.0799, Standard error (se): 0.0101, Z-score (h2/se): 7.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: paracetamol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_paracetamol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (62050 cases, 275109 controls)
Heritability (h2): 0.0708, Standard error (se): 0.00614, Z-score (h2/se): 11.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: perindopril (treatment/medication code), Trait category: Physical Health
Variable name: Medication_perindopril_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (4822 cases, 332337 controls)
Heritability (h2): 0.0819, Standard error (se): 0.0239, Z-score (h2/se): 3.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: ramipril (treatment/medication code), Trait category: Physical Health
Variable name: Medication_ramipril_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (15787 cases, 321372 controls)
Heritability (h2): 0.0912, Standard error (se): 0.0134, Z-score (h2/se): 6.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: salbutamol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_salbutamol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3972 cases, 333187 controls)
Heritability (h2): 0.0939, Standard error (se): 0.0249, Z-score (h2/se): 3.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: symbicort 100/6 turbohaler (treatment/medication code), Trait category: Physical Health
Variable name: Medication_symbicort_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2089 cases, 335070 controls)
Heritability (h2): 0.1536, Standard error (se): 0.0465, Z-score (h2/se): 3.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: Taking other prescription medications, Trait category: Physical Health
Variable name: Taking_other_prescription_medications_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336330 (158113 cases, 178217 controls)
Heritability (h2): 0.0703, Standard error (se): 0.00462, Z-score (h2/se): 15.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: thyroxine product (treatment/medication code), Trait category: Physical Health
Variable name: Medication_thyroxine_product_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3917 cases, 333242 controls)
Heritability (h2): 0.1448, Standard error (se): 0.044, Z-score (h2/se): 3.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: tramadol (treatment/medication code), Trait category: Physical Health
Variable name: Medication_tramadol_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3724 cases, 333435 controls)
Heritability (h2): 0.1412, Standard error (se): 0.0293, Z-score (h2/se): 4.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: ventolin 100micrograms inhaler (treatment/medication code), Trait category: Physical Health
Variable name: Medication_ventolin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (9712 cases, 327447 controls)
Heritability (h2): 0.1268, Standard error (se): 0.0179, Z-score (h2/se): 7.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Medication: warfarin (treatment/medication code), Trait category: Physical Health
Variable name: Medication_warfarin_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3404 cases, 333755 controls)
Heritability (h2): 0.1036, Standard error (se): 0.0342, Z-score (h2/se): 3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Migraine (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_migraine_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (10007 cases, 327152 controls)
Heritability (h2): 0.094, Standard error (se): 0.0161, Z-score (h2/se): 5.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: Bleeding gums, Trait category: Physical Health
Variable name: Mouth_etc_Bleeding_gums_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (43469 cases, 292669 controls)
Heritability (h2): 0.054, Standard error (se): 0.00673, Z-score (h2/se): 8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: Dentures, Trait category: Physical Health
Variable name: Mouth_etc_Dentures_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (56894 cases, 279244 controls)
Heritability (h2): 0.1084, Standard error (se): 0.00765, Z-score (h2/se): 14.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: Loose teeth, Trait category: Physical Health
Variable name: Mouth_etc_Loose_teeth_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (13238 cases, 322900 controls)
Heritability (h2): 0.0749, Standard error (se): 0.0138, Z-score (h2/se): 5.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: Mouth ulcers, Trait category: Physical Health
Variable name: Mouth_etc_Mouth_ulcers_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (34398 cases, 301740 controls)
Heritability (h2): 0.1001, Standard error (se): 0.0127, Z-score (h2/se): 7.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: None of the above, Trait category: Physical Health
Variable name: Mouth_etc_None_of_above_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (204310 cases, 131828 controls)
Heritability (h2): 0.0552, Standard error (se): 0.00437, Z-score (h2/se): 12.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Mouth/teeth dental problems: Painful gums, Trait category: Physical Health
Variable name: Mouth_etc_Painful_gums_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336138 (9287 cases, 326851 controls)
Heritability (h2): 0.0629, Standard error (se): 0.0151, Z-score (h2/se): 4.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Multiple Sclerosis, Trait category: Physical Health
Variable name: MultipleSclerosis_Sawcer2011, LDpred version: 1
Number of SNPs coordinated: 210382, Sample size: 27148 (9772 cases, 17376 controls)
Heritability (h2): 0.06, Standard error (se): 0.03, Z-score (h2/se): 2
Published study: https://www.ncbi.nlm.nih.gov/pubmed/21833088, Publication year: 2011
Trait: None of the above (blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy) diagnosed by doctor, Trait category: Physical Health
Variable name: No_diagnosis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336782 (228530 cases, 108252 controls)
Heritability (h2): 0.145, Standard error (se): 0.0123, Z-score (h2/se): 11.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Number of self-reported non-cancer illnesses, Trait category: Physical Health
Variable name: Number_of_self_reported_non_cancer_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199
Heritability (h2): 0.0577, Standard error (se): 0.00312, Z-score (h2/se): 18.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Other serious medical condition/disability diagnosed by doctor, Trait category: Physical Health
Variable name: Other_serious_diagnosed_by_doctor_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 331274 (67968 cases, 263306 controls)
Heritability (h2): 0.0597, Standard error (se): 0.00568, Z-score (h2/se): 10.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Note: reverse sign
Trait: Pain in throat and chest: diagnosis ICD10: R07 , Trait category: Physical Health
Variable name: Pain_in_throat_and_chest_ICD10_R07_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (16552 cases, 320647 controls)
Heritability (h2): 0.0932, Standard error (se): 0.0108, Z-score (h2/se): 8.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Back pain, Trait category: Physical Health
Variable name: Recent_Back_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (85221 cases, 251429 controls)
Heritability (h2): 0.078, Standard error (se): 0.00562, Z-score (h2/se): 13.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Facial pain, Trait category: Physical Health
Variable name: Recent_Facial_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (6118 cases, 330532 controls)
Heritability (h2): 0.0715, Standard error (se): 0.0222, Z-score (h2/se): 3.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Headache, Trait category: Physical Health
Variable name: Recent_Headache_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (66967 cases, 269683 controls)
Heritability (h2): 0.0877, Standard error (se): 0.00622, Z-score (h2/se): 14.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Hip pain, Trait category: Physical Health
Variable name: Recent_Hip_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (37714 cases, 298936 controls)
Heritability (h2): 0.0722, Standard error (se): 0.00671, Z-score (h2/se): 10.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Knee pain, Trait category: Physical Health
Variable name: Recent_Knee_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (71561 cases, 265089 controls)
Heritability (h2): 0.082, Standard error (se): 0.00616, Z-score (h2/se): 13.3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Neck or shoulder pain, Trait category: Physical Health
Variable name: Recent_Neck_or_shoulder_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (76404 cases, 260246 controls)
Heritability (h2): 0.0671, Standard error (se): 0.00536, Z-score (h2/se): 12.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: None of the above, Trait category: Physical Health
Variable name: Recent_None_of_the_above_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (136199 cases, 200451 controls)
Heritability (h2): 0.0898, Standard error (se): 0.00502, Z-score (h2/se): 17.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Pain all over the body, Trait category: Physical Health
Variable name: Recent_Pain_all_over_the_body_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (5099 cases, 331551 controls)
Heritability (h2): 0.137, Standard error (se): 0.0248, Z-score (h2/se): 5.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain type(s) experienced in last month: Stomach or abdominal pain, Trait category: Physical Health
Variable name: Recent_Stomach_or_abdominal_pain_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336650 (28098 cases, 308552 controls)
Heritability (h2): 0.0737, Standard error (se): 0.00881, Z-score (h2/se): 8.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain: Abdominal and pelvic pain: diagnosis ICD10: R10 , Trait category: Physical Health
Variable name: Abdominal_and_pelvic_pain_ICD10_R10_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (14203 cases, 322996 controls)
Heritability (h2): 0.0752, Standard error (se): 0.0123, Z-score (h2/se): 6.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain: Back pain for 3+ months, Trait category: Physical Health
Variable name: Back_pain_for_3_months_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 84489 (57893 cases, 26596 controls)
Heritability (h2): 0.0556, Standard error (se): 0.0139, Z-score (h2/se): 4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Pain: Neck/shoulder pain for 3+ months, Trait category: Physical Health
Variable name: Neck_shoulder_pain_for_3_months_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 75651 (52253 cases, 23398 controls)
Heritability (h2): 0.0604, Standard error (se): 0.0173, Z-score (h2/se): 3.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Parkinson's disease, Trait category: Physical Health
Variable name: Parkinsons_SimonSanchez2009, LDpred version: 1
Number of SNPs coordinated: 210404, Sample size: 5691 (1713 cases, 3978 controls)
Heritability (h2): 0.41, Standard error (se): 0.12, Z-score (h2/se): 3.4
Published study: https://www.ncbi.nlm.nih.gov/pubmed?cmd=DetailsSearch&term=19915575%5BPMID%5D, Publication year: 2009
Trait: Phlebitis and thrombophlebitis: diagnosis ICD10: I80 , Trait category: Physical Health
Variable name: Phlebitis_and_thrombophlebitis_ICD10_I80_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (1613 cases, 335586 controls)
Heritability (h2): 0.2534, Standard error (se): 0.0661, Z-score (h2/se): 3.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Respiratory: bring up phlegm/sputum/mucus on most days, Trait category: Physical Health
Variable name: Bring_up_phlegm_sputum_mucus_on_most_days_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 83529 (6998 cases, 76531 controls)
Heritability (h2): 0.1084, Standard error (se): 0.035, Z-score (h2/se): 3.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Respiratory: cough on most days, Trait category: Physical Health
Variable name: Cough_on_most_days_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 83529 (11424 cases, 72105 controls)
Heritability (h2): 0.1181, Standard error (se): 0.0267, Z-score (h2/se): 4.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Respiratory: emphysema/chronic bronchitis: diagnosed by doctor: , Trait category: Physical Health
Variable name: Emphysema_chronic_bronchitis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 336782 (5599 cases, 331183 controls)
Heritability (h2): 0.1336, Standard error (se): 0.0344, Z-score (h2/se): 3.9
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Respiratory: used an inhaler for chest within last hour, Trait category: Physical Health
Variable name: Used_an_inhaler_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 309688 (2245 cases, 307443 controls)
Heritability (h2): 0.1702, Standard error (se): 0.0444, Z-score (h2/se): 3.8
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Respiratory: wheeze or whistling in the chest in last year, Trait category: Physical Health
Variable name: Wheeze_or_whistling_in_the_chest_in_last_year_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 331257 (68531 cases, 262726 controls)
Heritability (h2): 0.1293, Standard error (se): 0.00695, Z-score (h2/se): 18.6
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Skin: eczema, Trait category: Physical Health
Variable name: Eczema_Paternoster2015, LDpred version: 1
Number of SNPs coordinated: 499077, Sample size: 116863 (21399 cases, 95464 controls)
Heritability (h2): 0.0709, Standard error (se): 0.0163, Z-score (h2/se): 4.3
Published study: https://www.ncbi.nlm.nih.gov/pubmed/26482879, Publication year: 2015
Trait: Skin: eczema/dermatitis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_eczema_dermatitis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (8718 cases, 328441 controls)
Heritability (h2): 0.0633, Standard error (se): 0.0209, Z-score (h2/se): 3
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Skin: psoriasis (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_psoriasis_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (3871 cases, 333288 controls)
Heritability (h2): 0.1089, Standard error (se): 0.0317, Z-score (h2/se): 3.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Surgery: had major operations, Trait category: Physical Health
Variable name: Had_major_operations_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 155045 (99647 cases, 55398 controls)
Heritability (h2): 0.0355, Standard error (se): 0.00872, Z-score (h2/se): 4.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Surgery: had other major operations, Trait category: Physical Health
Variable name: Had_other_major_operations_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 179567 (120566 cases, 59001 controls)
Heritability (h2): 0.0514, Standard error (se): 0.00834, Z-score (h2/se): 6.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Surgery: number of operations, self-reported, Trait category: Physical Health
Variable name: Number_of_operations_self_reported_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199
Heritability (h2): 0.0395, Standard error (se): 0.00319, Z-score (h2/se): 12.4
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Urogenital: kidney stone/ureter stone/bladder stone (non-cancer illness code, self-reported), Trait category: Physical Health
Variable name: self_reported_kidney_stone_etc_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337159 (2694 cases, 334465 controls)
Heritability (h2): 0.1629, Standard error (se): 0.0402, Z-score (h2/se): 4.1
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Urogenital: prostate: ever had prostate specific antigen (PSA) test, Trait category: Physical Health
Variable name: prostate_specific_antigen_PSA_test_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 147970 (46523 cases, 101447 controls)
Heritability (h2): 0.0503, Standard error (se): 0.00963, Z-score (h2/se): 5.2
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Urogenital: unspecified haematuria: diagnosis ICD10: R31 , Trait category: Physical Health
Variable name: Unspecified_haematuria_ICD10_R31_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (7363 cases, 329836 controls)
Heritability (h2): 0.0648, Standard error (se): 0.0186, Z-score (h2/se): 3.5
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017
Trait: Varicose veins of lower extremities: diagnosis ICD10: I83 , Trait category: Physical Health
Variable name: Varicose_veins_ICD10_I83_UKB2017, LDpred version: 1
Number of SNPs coordinated: 499422, Sample size: 337199 (6958 cases, 330241 controls)
Heritability (h2): 0.1803, Standard error (se): 0.0259, Z-score (h2/se): 7
Published study: http://www.nealelab.is/uk-biobank, Publication year: 2017